When new neighbors move next door, the Harper Quads are instantly drawn to Syd, the kid in their age. They spy on her and try to befriend her in hopes that she will let them hangout in her treehouse. However, Syd has already been warned to beware of the Harper Quads because of their reputation in the block.
- Lizzy Greene as Dawn Harper
- Casey Simpson as Ricky Harper
- Mace Coronel as Dicky Harper
- Aidan Gallagher as Nicky Harper
- Allison Munn as Anne Harper
- Ashley Liao as Syd
- Anne lists some of the shenanigans the Harper Quads have done in other episodes including:
- Starting a secret club in the garage that sent off a rodeo bull through the living room wall in No Ifs, Ands, or But-ers
- Getting kicked out of summer camp in Unhappy Campers
- Being banned from every doctor's office in the state in M.D. Day
- Breaking into Candice Parker's tour in I Want Candace
- Renting their garage to a rock band in Rock 'n' Rules
- Getting trapped in a dumpster in the mall in Mall in the Family
- Being banned from restaurants within 10 mile radius in Doggy Door Afternoon
- Having other characters list the bad things the quads have done becomes a recurring theme in Season 3 episodes including Quadshank Redemption, Quad for Teacher.
- The quads talk about how their lives are so adventurous that they could have a show about them. In Keeping Up With the Quadashians, they create their own reality show called Hanging with the Harpers.
- The quads debate about potential names for their show:
- Dawn suggests "DAWN... Nicky, Ricky, Dicky"
- Ricky suggests "Ricky, Dawn, Dicky, Nicky"
- Dicky says it would be "Dicky"
- Nicky says it would be called "Nicky, Ricky, Dicky & Dawn" but they laugh it.