Trish Harper is a sweet-hearted beloved woman. She is seen to be very nice and kind, although she is not very intelligent.
In What's the Worst That Quad Happen?, she brings back the Harper Quads to Tom and Anne. Later in the episode, Nicky, Dicky, Dawn, and Mae go sneak to get their present from Trish. Ricky attempts to stop them and gives the rest of the quads and Mae a story. At the end of the story, Trish is revealed to be the bike thief. She frames Nicky, Ricky, and Dicky. She lets Ricky not go to jail knowing he can't use the bathroom there. Tom, Anne, and Trish are revealed to have been listening to Ricky tell his story.
- The Quad-Test (mentioned)
- What's the Worst That Quad Happen?
- This Little Piggy Went to the Harpers (mentioned)
- She is the first Harper family member to be seen, the second being Jackie in QUADGOALS.
- It is revealed in It’s a Hard Knocks Life that she isn’t a very good chef/baker.
- She has only ever been mentioned in a few episodes, with appearing only on the episode, What's the Worst That Quad Happen?.
- She enjoys watching SpongeBob SquarePants.